35th BSCB GenSoc UK Cilia Network e-symposium
Date: November 16th 2021 Time: 15:00 - 17:30 BST
Kai Hao, graduate student, Zhu lab, Shanghai Institute of Biochemistry and Cell Biology, China "Cilia locally synthesize proteins to sustain their ultrastructure and functions." Ben Engel, PI, Biozentrum University of Basel, Switzerland "In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains." Sylwia Niedziółka, graduate student, Niewiadomski lab , Centre of New Technologies, University of Warsaw, Poland "The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium" Tiago Dantas, PI, Institute for Research and Innovation in Health (i3S), University of Porto, Portugal "WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing." Carla Sanjurjo-Soriano, post doc, Kalatzis lab, Institute for Neurosciences of Montpellier, Inserm, France"Unrevealing pathophysiology associated to USH2A mutations using CRISPR and iPSC-derived retinal organoids." Shu-Hsien Sheu, senior scientist, Clapham lab, Janelia Research Campus, US "A serotonergic axon-cilia synapse."
PAST CILIA EVENTS 2021
34th BSCB GenSoc UK Cilia Network e-symposium
Date: November 2nd 2021 Time: 15:00 - 17:30 GMT
Andreia Pinto, senior scientist, Hogg lab, Royal Brompton Hospital, UK "PCD-AID – How will Artificial Intelligence improve the diagnosis of Primary Ciliary Dyskinesia." Pierrick Le Borgne, graduate student, Tassin lab, Institut de Biologie intégrative de la cellule, France "The ternary complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly" Ann-Kathin Volz, graduate student, May-Simera lab, Johannes Gutenberg-Universität Mainz, Germany "Bardet-Biedl Syndrome Proteins Modulate the Release of Bioactive Extracellular Vesicles" Olivier Mercey, postdoc, Hamel and Guichard labs, University of Geneva, Switzerland "The connecting cilium inner scaffold provides a structural foundation to maintain photoreceptor integrity" Rebecca Poon, graduate student, Wan lab University of Exeter, UK"Metachronal coordination and ciliary propulsion in marine larvae" Peter Calvert, PI, SUNY Upstate Medical University, US"Functional compartmentalization of photoreceptor neurons"
33rd BSCB GenSoc UK Cilia Network e-symposium
Date: October 19th 2021 Time: 15:00 - 17:30 BST
It was almost a year exactly until our EMBO Cilia meeting is finally due to meet in person again in Cologne with our patient-based events kicking off the meeting! To mark this occasion, we ran an amazing place-holder session to bring together patients and patient advocacy groups to our researchers, something that has been missing from these e-symposia we normally run. The aim of this one-off session was to highlight what challenges and opportunities there are for PCD, PKD and BBS patients specifically, but perhaps in common to for the ciliopathies in general. We hoped to encourage and inspire researchers to be more engaged with patient support groups.
3:05 -3:25 Lucy Dixon, chair, PCD Support UK
3:25 - 3:45 Heymut Omran, Professor and Chief Medical Director of the Department of General Pediatrics at the University Hospital Muenster, Germany
3:45 - 4:05 Tonia Hymers, Service Manager for BBS UK and BBS UK Clinics Ltd.
4:05 - 4:25 Max Nachury, Ophthalmology, University of California San Francisco, US
4:25 - 4:45 Tess Harris, CEO of the PKD Charity UK
4:45 - 5:05 John Sayer, Deputy Dean of Clinical Medicine, Translational and Clinical Research Institute, University of Newcastle upon Tyne, UK
32nd BSCB GenSoc UK Cilia Network e-symposium
Date: September 21st 2021 Time: 15:00 - 17:30 BST
Gina LoMastro, graduate student, Holland lab (Johns Hopkins University School of Medicine, US) ‘Control of centriole amplification during multiciliogenesis.' Mayanka Awasthi, postdoc, Snell lab (University of Maryland, US) 'A Cytoplasmic Protein Kinase In Chlamydomonas Links An Adhesion Receptor-Activated Ciliary Signal To A cAMP-Mediated Cellular Response.' Sergio Gradilone,PI (The Hormel Institute, University of Minnesota, US) 'Primary Cilia in Cholangiocarcinoma: a Tumor Suppressor Organelle.' Jacob Anderson, graduate student, Brown lab (Harvard Medical School, US) 'Model of the Mammalian Ciliary Microtubule Doublet Reveals a Pentameric ODA-DC, a Luminal Filament, and the Structural Basis for the 48 to 24nm Repeating Register'. Priyanka Anujan, former postdoc, Bingle/Roy labs (Imperial College London, UK) 'Functional analysis of two novel paralogous microtubule inner proteins, Pierce1 and 2 using zebrafish.' Hannah Farley, former graduate student, Norris lab (MRC Harwell, UK) 'How mice help us understand the spectrum of ciliary dysmotility: microtubule inner proteins.'
31st BSCB GenSoc UK Cilia Network e-symposium
Date: August 24th 2021 Time: 15:00 - 17:30 BST
Hermes Bloomfield-Gadêlha, PI (University of Bristol, UK) ‘Resolving the riddle of how human sperm flagellum beats in 3D and its connection to cilia'. Fatmanur Tiryaki, graduate student, Firat Karalar lab (Koç University, TR) 'ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium assembly and Hedgehog signaling. Ivanna Williantarra, graduate student,McGlashan/Jensen lab (University of Aukland, NZ) 'Matrix stiffness controls ciliogenesis and centriole position.' Patricia Yeyati, senior scientist, Mill lab (MRC HGU, University of Edinburgh, UK) 'Investigating the role of translational control in motile ciliogenesis'. Nathalie Jurisch-Yaksi, PI (Norwegian University of Science and Technology, NO) 'Unravelling the spatio-temporal dynamics of ciliary beating in a multiciliated organ.'
29th BSCB GenSoc UK Cilia Network e-symposium
Date: July 13th 2021 Time: 15:00 - 17:30 GMT
Dan Jagger, PI (University College London, UK) ‘The inner ear as a readout of ciliopathy gene dysfunction'. Raj Ladher, PI (NCBS, Bangalore, IN) 'The role of cilia in the acquisition of a planar polarised auditory epithelium.' Abigail Moye, postdoc, Wensel lab (Baylor College of Medicine, US) 'Ultrastructural analysis of the Cep290 mutant axoneme in mouse photoreceptors. Gáspár Jékely, PI (University of Exeter, UK) 'Sensory and motile cilia in Platynereis larvae'. Susana Lopes, PI (NOVA Medical school- CEDOC, PT) 'Flow manipulations in the left-right organizer'. Antonio Feliciello, PI (University of Naples, IT) 'Coupling cAMP signaling to protein turnover in ciliogenesis and cancer'.
28th BSCB GenSoc UK Cilia Network e-symposium
Date: June 15th 2021 Time: 15:00 - 17:30 GMT
Fanni Gergely, PI (University of Oxford, UK) ‘Cell type-specific functions of mammalian centrosomes'. Alison Philbrook, postdoc, Sengupta lab, (Brandeis University, US) 'C. elegans sensory cilia architecture shapes olfactory response dynamics.' Sunayna Best, clinical researcher, Johnson lab (University of Leeds, UK) 'Molecular diagnoses identified amongst participants entered to the 100,000 Genomes Project with suspected primary ciliopathies'. Mia Konjikusic, graduate student, Gray/Wallingford labs(University of Texas at Austin, US) 'Kif9: A non-canonical ciliary kinesin'. Sumeda Nandadasa, PI (UMass Medical School, US) 'ADAMTS9 metalloproteinase modulation of the ciliary transition zone'.
27th BSCB GenSoc UK Cilia Network e-symposium
Date: June 1st 2021 Time: 15:00 - 17:30 GMT
Vadim Arshavsky, PI (Duke University, US) ‘How to build a light-sensitive organelle from a primary cilium' Will Spencer, postdoc, Arshavsky lab, (Duke University, US) 'PRCD is a small protein essential for high-fidelity photoreceptor disc formation.' Athullya Baby, graduate student, Kodjabachian lab (IBDM, Marseille, FR) 'Quantitative analysis and simulations of Cilia Driven Flow in vivo'. Stefaan Verbruggen, PI (University of Sheffield, UK) 'Osteocyte-cancer cell crosstalk regulates bone metastases - a feedback mechanism involving osteocyte primary cilia '. Noemie Gaudin, graduate student, Azimzadeh lab (Université de Paris - Institut Jacques Monod, FR) 'Evolutionary conservation of centriole rotational asymmetry in the human centrosome'. Steve King, PI (University of Connecticut Health Center, US) 'Dissecting a Cilia-based Peptidergic Signaling Pathway'
26th BSCB GenSoc UK Cilia Network e-symposium
Date: 18 May 2021 Time: 15:00 - 17:30 GMT
Chris Staples, PI (University of Bangor, UK) ‘The role of HERC2 in ciliogenesis'. Francesc Garcia-Gonzalo, PI (Autonomous University of Madrid, ES) 'Multiple ciliary localization signals control INPP5E ciliary targeting.' Karen Lange, Blacque lab, postdoc (University College Dublin, IE) 'Characterizing ciliopathy-associated variants of unknown significance (VUS) in TMEM67 using C. elegans'. Karl Lechtreck, PI (University of Georgia, US) 'PARMC2/PF27 is an obligate adapter for IFT of radial spokes.' Gaia Pigino, PI (Human Technopole, IT) 'Towards a mechanistic understanding of cilia biology by CLEM and cryo-ET'.
25th BSCB GenSoc UK Cilia Network e-symposium
Date: 04 May 2021 Time: 15:00 - 17:30 GMT
Mu He, PI (Faculty of Medicine, the University of Hong Kong, CN) 'From one to many: the making of a multiciliated cell.' Vikas Daggubati, MD-PhD candidate, Raleigh lab (UCSF, US) ‘Smoothened-activating lipids drive resistance to Hedgehog-associated medulloblastoma'. Fei Fang, postdoc, Thomopoulos lab (Columbia University, US) 'Cilia in tendon enthesis function as mechanosensing antennae.' Jaime Hibbard, Wallingford lab, PhD candidate (University of Texas at Austin, US) 'Diffusion-to-capture for peri-basal body retention of IFT proteins' Jay Gopalakrishnan, PI (Heinrich-Heine-Universität, DE) 'Cilium induction triggers differentiation of glioma stem cells '.
24th BSCB GenSoc UK Cilia Network e-symposium
Date: 20 April 2021 Time: 15:00 - 17:30 GMT Priyanka Singh, PI (Indian Institute of Technology Jodhpur, India) 'Polo-like kinase: Staying connected while being apart'. Roly Megaw, clinician scientist, Mill lab (MRC Human Genetics Unit, UK) ‘Building a photoreceptor: A role for RPGR in disc formation'. Inna Nikonorova, postdoc, Barr lab (Rutgers University, US) 'Deciphering ciliary EV proteome of C. elegans.' Daniel Kopinke, PI (University of Florida, US) 'Ciliary control of fatty fibrosis: Friend or Foe?. Johanna Höog, PI (University of Gothenburg, SE) 'TAILS of a sperm cell' John Wallingford, PI (University of Texas at Austin, US) 'DynAPs: Novel liquid-like organelles for axonemal dynein assembly (we think) '.
23rd BSCB GenSoc UK Cilia Network e-symposium
Date: 23 March 2021 Time: 15:00 - 17:30 GMT
Helen May-Simera, PI (Johannes Gutenberg-Universität Mainz, DE) 'Cilia in the RPE- And how they help us to see'. Maneesha Pandey, recently defended PhD student, He lab (National University of Singapore, SG) 'Functional Lipidated protein Intraflagellar Transport (LIFT) pathway in Trypanosoma brucei'. Melissa LaBonty, postdoc, Yoder lab (University of Alabama at Birmingham, US) 'Conservation of the genetic interaction between bbs-5 and nphp-4 across species.' Jennifer Lennon, PhD student, Jarman lab (University of Edinburgh, UK) 'Investigating R2TP-like complexes in Drosophila motile ciliated cells'. Manu Prakash, PI (Stanford University, US) 'Walk, Run and Swim: Wonderland of ciliary biophysics '.
22nd BSCB GenSoc UK Cilia Network e-symposium
Date: 09 March 2021 Time: 15:00 - 17:30 GMT
3:05 -3:25 Susana Godhino, PI (Queen Mary University London, UK) 'Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption'. 3:25 -3:45 Melis Dilara Arslanhan, graduate student, Fırat Karalar lab (Koç University, TR) 'Aurora Kinase A proximity interactome reveals centriolar satellites as regulators of its function at the primary cilium'. Long Gui, postdoc, Nicastro lab (University of Texas Southwestern Medical Center, US) 'Cryo-electron tomography of Drosophila sperm flagella.' 4:05 - 4:25 Laura Bozal-Basterra, recently defended graduate student, Barrio lab (CIC bioGUNE, ES) 'LUZP1, a novel regulator of primary cilia and the actin cytoskeleton, is a contributing factor in Townes-Brocks Syndrome and cancer'. 4:25 - 4:45 Juan Wang, postdoc, Barr lab (Rutgers University, US) 'Sensory cilia act as a specialized venue for regulated extracellular vesicles biogenesis and signaling.' 4:45 - 5:05 Tim Stearns, PI (Stanford University, US) 'The frangible flagellum of frugal fungi'.
21st BSCB GenSoc UK Cilia Network e-symposium
Date: 23 February 2021 Time: 15:00 - 17:30 GMT
Jeroen Dobblelaere, postdoc, Dammerman lab (Max Perutz Labs, Vienna, AT) 'Identification of novel ciliogenesis genes in Drosophila and C. elegans'. Saurabh Kulkarni, PI (Univeristy of Virginia, US) 'Control of multiciliated cell assembly.' Qinhui Rao, postdoc, Zhang Lab (Yale University, US) 'Cryo-EM structures of outer-arm dynein array bound to microtubule doublet reveal a mechanism for motor coordination'. Elkhan Yusifov, graduate student, Stoeckli Lab (University of Zurich, CH) 'Investigating the role of primary cilia during neural circuit formation.' Keren Hilgendorf, PI (University of Utah, US) 'CCiliation of muscle stem cells is critical for muscle regeneration and lost during aging'.
20th BSCB GenSoc UK Cilia Network e-symposium
Date: 09 February 2021 Time: 15:00 - 17:30 GMT
Uwe Wolfrum, (Johannes Gutenberg University of Mainz, Institute of Molecular Physiology, DE) 'Photoreceptor cilia in health and disease'. Mustafa Pir, postdoc, Kaplan lab (Abdullah Gul University, TR) 'ConVarT: a search tool for orthologous variants and functional inference of human genetic variants'. Haotian Zhao, (New York Institute of Technology, College of Osteopathic Medicine) 'Disruption of the GEMC1-MCIDAS transcriptional program promotes choroid plexus carcinoma'. Mathieu Bottier, postdoc, Chalmers Lab (University of Dundee, UK) 'Impact of inflammatory cytokines on mucociliary clearance'. Katie Ching, graduate student, Stearns Lab (Stanford University, US) 'Making and moving centrioles in the olfactory epithelium.' Matt Sarkisian, PI (University of Florida, US) 'Ciliary vesicle-mediated SHH signaling in glioblastoma'.
19th BSCB GenSoc UK Cilia Network e-symposium
Date: 26 January 2021 Time: 15:00 - 17:30 GMT
Issei Shimada, junior associate professor, (Nagoya City University, JP) 'Gpr161 regulates neural stem cells and cancer'. Brae Bigge, graduate student, Avasthi labs (Dartmouth University, US) 'Initial ciliary assembly in Chlamydomonas requires Arp2/3-dependent recruitment from a ciliary protein reservoir in the plasma membrane'. Girish Mali, postdoc, Carter lab (MRC Laboratory of Molecular Biology, UK) 'Characterising novel regulators of axonemal outer dynein arms'. Rachel Turn, graduate student, Kahn Lab (Emory University, US) 'Roles for ELMOD2 and Rootletin in Ciliogenesis'. Rob Mahen, postdoc (Hutchison MRC Research Centre, University of Cambridge, UK) 'Centrosome-distal rootlet termini dynamically mediate centrosome-organelle interactions.' Ruxandra Bachmann, PI (University of Zurich, CH) 'The Bardet-Biedl protein BBS1 controls protein and lipid composition of photoreceptor outer segments in zebrafish'.
18th BSCB GenSoc UK Cilia Network e-symposium
Date: 12 January 2021 Time: 15:00 - 17:30 GMT
Muneyoshi Ichikawa, assistant professor, (Nara Institute of Science and Technology, JP) 'Remodeling and activation mechanisms of outer arm dynein revealed by cryo-EM'. Sónia Gomes Pereira, graduate student, Bettencourt-Dias/Becker labs (Instituto Gulbenkian de Ciência, PT) 'Asymmetrical maturation of de novo assembled twin centrioles' . Monica Veneres, PI(Ohio State University, US) 'KIF11/Eg5: A mitotic motor moonlighting at primary cilia'. Alexandre Dumoulin, postdoc, Stoeckli Lab (University of Zurich, CH) 'A cell-autonomous role for primary cilia in the long-range guidance of commissural axons'. Thao Phan, graduate student, Holland Lab (Johns Hopkins University Medical School, US) 'Centrosome defects cause microcephaly by activating the 53BP1‐USP28‐TP53 mitotic surveillance pathway.' Philippe Bastin, PI (Institut Pasteur,FR) 'IFT train positioning: the key in shaping different types of cilia and flagella?"'.